Purified by DEAE column chromatography and presented liquid in 0.015M potassium phosphate, 0.85% NaCl, pH 7.2.
PURITY
>90% by SDS-PAGE
IMMUNOGEN
Recombinant Zika NS1 protein
APPLICATION
Potentially suitable for ELISA and rapid lateral flow application for detection of Zika NS1 protein
PRESERVATIVE
0.05% sodium azide
STORAGE
+2°C to +8°C
REFERENCES
Efficacy of the broad-spectrum antiviral compound BCX4430 against Zika virus in cell culture and in a mouse model. Julander J, Siddharthan V, Evans J et al. Antiviral Research. 2017 vol: 137 pp: 14-22
Zika virus infection of adult and fetal STAT2 knock-out hamsters Siddharthan V, Van Wettere A, Li R, Miao J, Wang Z et. al. Virology. 2017 vol: 507 pp: 89-95
Cell-line dependent antiviral activity of sofosbuvir against Zika virus Mumtaz N, Jimmerson L, Bushman L, Kiser J, Aron G et. al. Antiviral Research. 2017 vol: 146 pp: 161-163
A Zika vaccine targeting NS1 protein protects immunocompetent adult mice in a lethal challenge model Brault A C, Domi A, McDonald E M, Kiser J, Talmi-Frank D. et al. Nature. 2017 Scientifc Reports vol: 14769